Cover letter 2

Dear Dr. Byrne

We are submitting the article: "DlgS97 is essential for short term memory in Drosophila", authored by Carlos Oliva and Jimena Sierralta, so that you consider its publication Learning and Memory.
We believe that this study is potentially interesting for Learning and Memory readers, because it shows, for the first time an in vivo role of Dlg in the memory storage; since the complete mutation of dlg gene is lethal, precluding any intent of performing this kind of study. We used a mutant of a specific splicing variant that knocks out just one of the two products of the dlg gene. This mutant is viable and has not defects in the basic brain architecture.
The manuscript has been written and approved by both authors.
This study has not been submitted for publication elsewhere, and to our knowledge there is no conflict of interests.

Sincerely

Carlos Oliva PhD Student
Physiology and Biophysics department
Faculty of Medicine
University of Chile
Ph: 56-2-9786033
coliva@med.uchile.cl

Commentary about creativity

In my point of view Mr. Roberson is right in several ways; however we have to be carefully and do not make the inverse mistake. I mean, put all the children in some kind of school only for arts. I think creativity is not only in arts, but also in mathematics and science. Maybe a good way to improve the current model is to implement an educational system, where in the first years the teachers find what talents the children have and then use specific curses to potentiate them.
In respect of the article creativity and mental health, it is very interesting. But I think that should be more factors involve that just expression of dopamine receptors. Indeed seems like that the activity of the Thalamus is the key factor. Any way the article support the general notion that people very creative is also a little crazy.

Cover letter 1

Dear Dr. Byrne

We are submitting our article: "DlgS97 is essential for short term memory in Drosophila", by the authors Carlos Oliva and Jimena Sierralta, so that you consider its publication in your prestigious journal Learning and Memory. The manuscript has been written and approved by all of the authors. Our study is not under consideration at any other journal for publication and we have not conflict of interest.
We think that our study is potentially interesting for Learning and Memory readers, because it shows for the first time an in vivo role of Dlg in the memory storage. Since the complete mutation of dlg gene is lethal, precluding any intent of perform this kind of study, we used a mutant of a specific splicing variant that knock out just one of the two products of the dlg gene. This mutant is viable and has not defects in the basic brain architecture.

Sincerely

Carlos Oliva PhD Student
Physiology and Biophysics department
Faculty of Medicine
University of Chile